Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Slc6a4  solute carrier family 6 (neurotransmitter transporter, serotonin), member 4   (Synonyms: 5-HTT, Htt, Sert)
Results	Reference
1	J:312428 Adams EJ, Khoriaty R, Kiseleva A, Cleuren ACA, Tomberg K, van der Ent MA, Gergics P, Tang VT, Zhu G, Hoenerhoff MJ, O'Shea KS, Saunders TL, Ginsburg D, Murine SEC24D can substitute functionally for SEC24C during embryonic development. Sci Rep. 2021 Oct 26;11(1):21100
1	J:138764 Arnold SJ, Huang GJ, Cheung AF, Era T, Nishikawa S, Bikoff EK, Molnar Z, Robertson EJ, Groszer M, The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone. Genes Dev. 2008 Sep 15;22(18):2479-84
1*	J:184980 Assimacopoulos S, Kao T, Issa NP, Grove EA, Fibroblast growth factor 8 organizes the neocortical area map and regulates sensory map topography. J Neurosci. 2012 May 23;32(21):7191-201
1	J:322808 Castanza AS, Ramirez S, Tripathi PP, Daza RAM, Kalume FK, Ramirez JM, Hevner RF, AUTS2 Regulates RNA Metabolism and Dentate Gyrus Development in Mice. Cereb Cortex. 2021 Aug 26;31(10):4808-4824
1	J:316684 Ding Q, Balasubramanian R, Zheng D, Liang G, Gan L, Barhl2 Determines the Early Patterning of the Diencephalon by Regulating Shh. Mol Neurobiol. 2017 Aug;54(6):4414-4420
1	J:196080 Elsen GE, Hodge RD, Bedogni F, Daza RA, Nelson BR, Shiba N, Reiner SL, Hevner RF, The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
1	J:310330 Forero A, Rivero O, Waldchen S, Ku HP, Kiser DP, Gartner Y, Pennington LS, Waider J, Gaspar P, Jansch C, Edenhofer F, Resink TJ, Blum R, Sauer M, Lesch KP, Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain. Front Cell Neurosci. 2017;11:307
1*	J:165534 Funato H, Sato M, Sinton CM, Gautron L, Williams SC, Skach A, Elmquist JK, Skoultchi AI, Yanagisawa M, Loss of Goosecoid-like and DiGeorge syndrome critical region 14 in interpeduncular nucleus results in altered regulation of rapid eye movement sleep. Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18155-60
1*	J:174479 Gil V, Bichler Z, Lee JK, Seira O, Llorens F, Bribian A, Morales R, Claverol-Tinture E, Soriano E, Sumoy L, Zheng B, Del Rio JA, Developmental expression of the oligodendrocyte myelin glycoprotein in the mouse telencephalon. Cereb Cortex. 2010 Aug;20(8):1769-79
1	J:81450 Hendricks TJ, Fyodorov DV, Wegman LJ, Lelutiu NB, Pehek EA, Yamamoto B, Silver J, Weeber EJ, Sweatt JD, Deneris ES, Pet-1 ETS Gene Plays a Critical Role in 5-HT Neuron Development and Is Required for Normal Anxiety-like and Aggressive Behavior. Neuron. 2003 Jan 23;37(2):233-47
1	J:144066 Joshi PS, Molyneaux BJ, Feng L, Xie X, Macklis JD, Gan L, Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex. Neuron. 2008 Oct 23;60(2):258-72
1*	J:151979 Katori S, Hamada S, Noguchi Y, Fukuda E, Yamamoto T, Yamamoto H, Hasegawa S, Yagi T, Protocadherin-alpha family is required for serotonergic projections to appropriately innervate target brain areas. J Neurosci. 2009 Jul 22;29(29):9137-47
1	J:94202 Kusserow H, Davies B, Hortnagl H, Voigt I, Stroh T, Bert B, Deng DR, Fink H, Veh RW, Theuring F, Reduced anxiety-related behaviour in transgenic mice overexpressing serotonin 1A receptors. Brain Res Mol Brain Res. 2004 Oct 22;129(1-2):104-16
1	J:119936 Manuel M, Georgala PA, Carr CB, Chanas S, Kleinjan DA, Martynoga B, Mason JO, Molinek M, Pinson J, Pratt T, Quinn JC, Simpson TI, Tyas DA, van Heyningen V, West JD, Price DJ, Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization. Development. 2007 Feb;134(3):545-55
1	J:310971 Mercurio S, Serra L, Motta A, Gesuita L, Sanchez-Arrones L, Inverardi F, Foglio B, Barone C, Kaimakis P, Martynoga B, Ottolenghi S, Studer M, Guillemot F, Frassoni C, Bovolenta P, Nicolis SK, Sox2 Acts in Thalamic Neurons to Control the Development of Retina-Thalamus-Cortex Connectivity. iScience. 2019 May 31;15:257-273
1	J:184976 Narboux-Neme N, Goiame R, Mattei MG, Cohen-Tannoudji M, Wassef M, Integration of H-2Z1, a Somatosensory Cortex-Expressed Transgene, Interferes with the Expression of the Satb1 and Tbc1d5 Flanking Genes and Affects the Differentiation of a Subset of Cortical Interneurons. J Neurosci. 2012 May 23;32(21):7287-7300
1	J:322680 Sato H, Hatakeyama J, Iwasato T, Araki K, Yamamoto N, Shimamura K, Thalamocortical axons control the cytoarchitecture of neocortical layers by area-specific supply of VGF. Elife. 2022 Mar 15;11:e67549
1	J:264182 Shehabeldin R, Lutz D, Karsak M, Frotscher M, Krieglstein K, Sharaf A, Reelin controls the positioning of brainstem serotonergic raphe neurons. PLoS One. 2018;13(7):e0200268
1	J:228291 Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H, Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Nat Commun. 2015;6:10232
1	J:339312 Sinclair-Wilson A, Lawrence A, Ferezou I, Cartonnet H, Mailhes C, Garel S, Lokmane L, Plasticity of thalamocortical axons is regulated by serotonin levels modulated by preterm birth. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2301644120
1*	J:186020 Takemoto M, Hattori Y, Zhao H, Sato H, Tamada A, Sasaki S, Nakajima K, Yamamoto N, Laminar and areal expression of unc5d and its role in cortical cell survival. Cereb Cortex. 2011 Aug;21(8):1925-34
1	J:160732 Thomson RE, Kind PC, Graham NA, Etherson ML, Kennedy J, Fernandes AC, Marques CS, Hevner RF, Iwata T, Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex. Neural Dev. 2009;4:4
1	J:56671 Upton AL, Salichon N, Lebrand C, Ravary A, Blakely R, Seif I, Gaspar P, Excess of serotonin (5-HT) alters the segregation of ispilateral and contralateral retinal projections in monoamine oxidase A knock-out mice: possible role of 5-HT uptake in retinal ganglion cells during development. J Neurosci. 1999 Aug 15;19(16):7007-24
1*	J:302618 Wang B, Iyengar R, Li-Harms X, Joo JH, Wright C, Lavado A, Horner L, Yang M, Guan JL, Frase S, Green DR, Cao X, Kundu M, The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway. Autophagy. 2018;14(5):796-811